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1

Heteromerization of chemokine (C-X-C motif) receptor 4 with α 1A/B -adrenergic receptors controls α 1 -adrenergic receptor function

Tripathi, Abhishek, Vana, P. Geoff, Chavan, Tanmay S., Brueggemann, Lioubov I., Byron, Kenneth L., Tarasova, Nadya I., Volkman, Brian F., Gaponenko, Vadim, Majetschak, Matthias

Journal:

Proceedings of the National Academy of Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2015

2

Pooled screening for antiproliferative inhibitors of protein-protein interactions

Nim, Satra, Jeon, Jouhyun, Corbi-Verge, Carles, Seo, Moon-Hyeong, Ivarsson, Ylva, Moffat, Jason, Tarasova, Nadya, Kim, Philip M

Journal:

Nature Chemical Biology

Année:

2016

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2016

3

SAVI, in silico generation of billions of easily synthesizable compounds through expert-system type rules

Patel, Hitesh, Ihlenfeldt, Wolf-Dietrich, Judson, Philip N., Moroz, Yurii S., Pevzner, Yuri, Peach, Megan L., DelannÃ©e, Victorien, Tarasova, Nadya I., Nicklaus, Marc C.

Journal:

Scientific Data

Année:

2020

Fichier:

PDF, 2.57 MB

2020

4

Peptide Structure Stabilization by Membrane Anchoring and its General Applicability to the Development of Potent Cell-Permeable Inhibitors

Liv Johannessen, Jarrett Remsberg, Prof. Vadim Gaponenko, Dr. Kristie M. Adams, Dr. Joseph J. Barchi Jr., Dr. Sergey G. Tarasov, Dr. Sheng Jiang, Dr. Nadya I. Tarasova

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 435 KB

english, 2011

5

Crystal structure of human pepsin and its complex with pepstatin

Masao Fujinaga, Maia M. Chernaia, Steve C. Mosimann, Michael N.G. James, Nadya I. Tarasova

Journal:

Protein Science

Année:

1995

Langue:

english

Fichier:

PDF, 2.64 MB

english, 1995

6

Anti-peptide antibodies specific for the gastrin/cholecystokinin-B receptor

Nadya I. Tarasova, Terry D. Copeland, David W. Farnsworth, Stephen A. Wank, Eric A. Hudson, James H. Resau, Christopher J. Michejda

Journal:

International Journal of Peptide Research and Therapeutics

Année:

1995

Langue:

english

Fichier:

PDF, 765 KB

english, 1995

7

Synthesis and properties of three fluorescent derivatives of gastrin

Grzegorz Czerwinski, Stephen A. Wank, Nadya I. Tarasova, Eric A. Hudson, James H. Resau, Christopher J. Michejda

Journal:

International Journal of Peptide Research and Therapeutics

Année:

1995

Langue:

english

Fichier:

PDF, 626 KB

english, 1995

8

Endocytosis of gastrin in cancer cells expressing gastrin/CCK-B receptor

Nadya I. Tarasova, Stephen A. Wank, Eric A. Hudson, Victor I. Romanov, Grzegorz Czerwinski, James H. Resau, Christopher J. Michejda

Journal:

Cell and Tissue Research

Année:

1997

Langue:

english

Fichier:

PDF, 1.55 MB

english, 1997

9

Synthesis and biological activity of 5-aza-ellipticine derivatives

Deborah L. Moody, Marcin Dyba, Teresa Kosakowska-Cholody, Nadya I. Tarasova, Christopher J. Michejda

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2007

Langue:

english

Fichier:

PDF, 385 KB

english, 2007

10

Transferrin conjugates of doxorubicin: Synthesis, characterization, cellular uptake, and in vitro efficacy

Felix Kratz, Ulrich Beyer, Thomas Roth, Nadya Tarasova, Philippe Collery, Francoise Lechenault, Annie Cazabat, Peter Schumacher, Clemens Unger, Ulrich Falken

Journal:

Journal of Pharmaceutical Sciences

Année:

1998

Langue:

english

Fichier:

PDF, 148 KB

english, 1998

11

Numerous cell targets for gastrin in the guinea pig stomach revealed by gastrin/CCKBreceptor localization

Nadya I. Tarasova, Victor I. Romanov, Pedro Pinto Da Silva, Christopher J. Michejda

Journal:

Cell and Tissue Research

Année:

1995

Langue:

english

Fichier:

PDF, 1001 KB

english, 1995

12

STAT1 activation regulates proliferation and differentiation of renal progenitors

Honghe Wang, Yili Yang, Nirmala Sharma, Nadya I. Tarasova, Olga A. Timofeeva, Robin T. Winkler-Pickett, Shunsuke Tanigawa, Alan O. Perantoni

Journal:

Cellular Signalling

Année:

2010

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2010

13

Intracellular localization of 7-benzylamino-6-chloro-2-piperazino-4-pyrrolidino-pteridine in membrane structures impeding the inhibition of cytosolic cyclic AMP-specific phosphodiesterase

Doris Marko, Karl-Heinz Merz, Claudia Kunz, Anja Müller, Nadya Tarasova, Gerhard Eisenbrand

Journal:

Biochemical Pharmacology

Année:

2002

Langue:

english

Fichier:

PDF, 290 KB

english, 2002

14

Direct Visualization of HIV-1 Entry: Mechanisms and Role of Cell Surface Receptors

Roland H. Stauber, Shen Rulong, Gottfried Palm, Nadya I. Tarasova

Journal:

Biochemical and Biophysical Research Communications

Année:

1999

Langue:

english

Fichier:

PDF, 467 KB

english, 1999

15

Crystal and Molecular Structures of Human Progastricsin at 1.62 Å Resolution

Stanley A. Moore, Anita R. Sielecki, Maia M. Chernaia, Nadya I. Tarasova, Michael N.G. James

Journal:

Journal of Molecular Biology

Année:

1995

Langue:

english

Fichier:

PDF, 1.61 MB

english, 1995

16

Bombesin marine toxin conjugates inhibit the growth of lung cancer cells

Terry W. Moody, Tapas Pradhan, Samuel A. Mantey, Robert T. Jensen, Marcin Dyba, Deborah Moody, Nadya I. Tarasova, Christopher J. Michejda

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 347 KB

english, 2008

17

Wnt4 induces nephronic tubules in metanephric mesenchyme by a non-canonical mechanism

Shunsuke Tanigawa, Honghe Wang, Yili Yang, Nirmala Sharma, Nadya Tarasova, Rieko Ajima, Terry P. Yamaguchi, Luis G. Rodriguez, Alan O. Perantoni

Journal:

Developmental Biology

Année:

2011

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2011

18

Gastrin released in response to meal stimulation regulates renal sodium excretion through inositol phosphate turnover (IP) and inhibition of Na+K+ ATPase

Joseph R Pisegna, Nadya I Tarasova, Jeffrey A Kopp, Lawrence D Asico, Xaio X Li, Christopher J Michejda, Pedro A Jose, Stephen A Wank

Journal:

Regulatory Peptides

Année:

2000

Langue:

english

Fichier:

PDF, 139 KB

english, 2000

19

Gastrin receptor expression and function during rapid transformation of the enterochromaffin-like cells in an African rodent

Laura H Tang, Eileen A Luque, Jason A Efstathiou, Kerem H Bortecen, Mark Kidd, Nadya I Tarasova, Irvin M Modlin

Journal:

Regulatory Peptides

Année:

1997

Langue:

english

Fichier:

PDF, 796 KB

english, 1997

20

Deletion of functional gastrin gene markedly increases colon carcinogenesis in response to azoxymethane in mice

Stephanie Cobb, Thomas Wood, Lino Tessarollo, Marco Velasco, Randall Given, Andrea Varro, Nadya Tarasova, Pomila Singh

Journal:

Gastroenterology

Année:

2002

Langue:

english

Fichier:

PDF, 552 KB

english, 2002

21

Transmembrane Inhibitors of P-Glycoprotein, an ABC Transporter

Tarasova, Nadya I., Seth, Rishi, Tarasov, Sergey G., Kosakowska-Cholody, Teresa, Hrycyna, Christine A., Gottesman, Michael M., Michejda, Christopher J.

Journal:

Journal of Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 425 KB

english, 2005

22

Mutational Analysis of ABCG2: Role of the GXXXG Motif

Polgar, Orsolya, Robey, Robert W., Morisaki, Kuniaki, Dean, Michael, Michejda, Christopher, Sauna, Zuben E., Ambudkar, Suresh V., Tarasova, Nadya, Bates, Susan E.

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 258 KB

english, 2004

23

Rationally Designed Inhibitors Identify STAT3 N-Domain as a Promising Anticancer Drug Target

Timofeeva, Olga A., Gaponenko, Vadim, Lockett, Stephen J., Tarasov, Sergey G., Jiang, Sheng, Michejda, Christopher J., Perantoni, Alan O., Tarasova, Nadya I.

Journal:

ACS Chemical Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2007

24

Cholecystokinin type B receptors (CCKBRS) in the rat kidneymediate gastrin-stimulated urinarysodium excretion through inositol phosphate turnover (IP) and inhibition of Na+/K+ ATPase

Pisegna, Joseph R., Tarasova, Nadya I., Kopp, Jeffrey A., Asico, Lawrence D., Li, Xaio X., Stalter, James, Michejda, Christopher J., Jose, Pedro A., Wank, Stephen A.

Journal:

Gastroenterology

Année:

2000

Langue:

english

Fichier:

PDF, 198 KB

english, 2000

25

Cytotoxic Agents Directed to Peptide Hormone Receptors: Defining the Requirements for a Successful Drug

Grzegorz Czerwinski, Nadya I. Tarasova and Christopher J. Michejda

Journal:

Proceedings of the National Academy of Sciences

Année:

1998

Langue:

english

Fichier:

PDF, 1.18 MB

english, 1998

26

Structural Analogues of Smoothened Intracellular Loops as Potent Inhibitors of Hedgehog Pathway and Cancer Cell Growth

Remsberg, Jarrett R., Lou, Hong, Tarasov, Sergey G., Dean, Michael, Tarasova, Nadya I.

Journal:

Journal of Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 184 KB

english, 2007

27

Optimization of Naphthalimide-imidazoacridone with Potent Antitumor Activity Leading to Clinical Candidate (HKH40A, RTA 502)

Hariprakasha, Humcha K., Kosakowska-Cholody, Teresa, Meyer, Colin, Cholody, Wieslaw M., Stinson, Sherman F., Tarasova, Nadya I., Michejda, Christopher. J.

Journal:

Journal of Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 106 KB

english, 2007

28

Mutational Analysis of Threonine 402 Adjacent to the GXXXG Dimerization Motif in Transmembrane Segment 1 of ABCG2

Polgar, Orsolya, Ierano, Caterina, Tamaki, Akina, Stanley, Bradford, Ward, Yvona, Xia, Di, Tarasova, Nadya, Robey, Robert W., Bates, Susan E.

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 4.61 MB

english, 2010

29

In Memoriam: Christopher J. Michejda (December 19, 1937−January 9, 2007)

Tarasova, Nadya I., Loeppky, Richard N., Byrd, R. Andrew, Keefer, Larry K.

Journal:

Chemical Research in Toxicology

Année:

2007

Langue:

english

Fichier:

PDF, 148 KB

english, 2007

30

Receptor antagonists targeting transmembrane domains

Tarasova, Nadya I

Journal:

Expert Opinion on Emerging Drugs

Année:

2000

Langue:

english

Fichier:

PDF, 5.08 MB

english, 2000

31

Mechanisms of Membrane Binding of Small GTPase K-Ras4B Farnesylated Hypervariable Region

Jang, Hyunbum, Abraham, Sherwin J., Chavan, Tanmay S., Hitchinson, Ben, Khavrutskii, Lyuba, Tarasova, Nadya I., Nussinov, Ruth, Gaponenko, Vadim

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.29 MB

english, 2015

32

Mechanisms of Unphosphorylated STAT3 Transcription Factor Binding to DNA

Timofeeva, Olga A., Chasovskikh, Sergey, Lonskaya, Irina, Tarasova, Nadya I., Khavrutskii, Lyuba, Tarasov, Sergey G., Zhang, Xueping, Korostyshevskiy, Valeriy R., Cheema, Amrita, Zhang, Lihua, Dakshan

Journal:

Journal of Biological Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2012

33

Protein Purification-free Method of Binding Affinity Determination by Microscale Thermophoresis

Khavrutskii, Lyuba, Yeh, Joanna, Timofeeva, Olga, Tarasov, Sergey G., Pritt, Samuel, Stefanisko, Karen, Tarasova, Nadya

Journal:

Journal of Visualized Experiments

Année:

2013

Langue:

english

Fichier:

PDF, 384 KB

english, 2013

34

Alternative ways of modulating JAK-STAT pathway

Timofeeva, Olga A., Tarasova, Nadya I.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 2.67 MB

english, 2012

35

Elucidating the Functional Significance of the C-Terminal Hypervariable Region (HVR) in K-Ras4A

Chakrabarti, Mayukh, Lu, Shaoyong, Jang, Hyunbum, Khavrutskii, Lyuba, Tarasova, Nadya I., Gaponenko, Vadim, Nussinov, Ruth

Journal:

Biophysical Journal

Année:

2015

Langue:

english

Fichier:

PDF, 63 KB

english, 2015

36

The structure of monomeric components of self-assembling CXCR4 antagonists determines the architecture of resulting nanostructures

Lee, Youngshim, Chen, Yuhong, Tarasova, Nadya I, Gaponenko, Vadim

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2011

37

Distribution and Localization of a Novel Cholecystokinin-Releasing Factor in the Rat Gastrointestinal Tract 1

Tarasova, Nadya, Spannagel, Alan W., Green, Gary M., Gomez, Guillermo, Reed, Jason T., Thompson, James C., Hellmich, Mark R., Reeve, Joseph R., Liddle, Rodger A., Greeley, George H.

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 840 KB

english, 1997

38

Development of a Novel Peptide Nanoparticle Inhibitor for Human CCR3/Eotaxin-Mediated Eosinophil Migration

Laffey, Kimberly G., Garnier, Boris, Hitchinson, Ben, Tarasova, Nadya, Gaponenko, Vadim, Ackerman, Steven J.

Journal:

Journal of Allergy and Clinical Immunology

Année:

2015

Langue:

english

Fichier:

PDF, 39 KB

english, 2015

39

Structural plasticity of a transmembrane peptide allows self-assembly into biologically active nanoparticles

Sergey G. Tarasov, Vadim Gaponenko, O. M. Zack Howard, Yuhong Chen, Joost J. Oppenheim, Marzena A. Dyba, Sriram Subramaniam, Youngshim Lee, Christopher Michejda and Nadya I. Tarasova

Journal:

Proceedings of the National Academy of Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2011

40

High-Affinity Interaction of the K-Ras4B Hypervariable Region with the Ras Active Site

Chavan, Tanmay S., Jang, Hyunbum, Khavrutskii, Lyuba, Abraham, Sherwin J., Banerjee, Avik, Freed, Benjamin C., Johannessen, Liv, Tarasov, Sergey G., Gaponenko, Vadim, Nussinov, Ruth, Tarasova, Nadya I

Journal:

Biophysical Journal

Année:

2015

Langue:

english

Fichier:

PDF, 2.78 MB

english, 2015

41

A new role for STAT3 as a regulator of chromatin topology

Zhao, Yunjie, Zeng, Chen, Tarasova, Nadya I, Chasovskikh, Sergey, Dritschilo, Anatoly, Timofeeva, Olga A

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 808 KB

english, 2013

42

Mycobacterium tuberculosis copper-regulated protein SocB is an intrinsically disordered protein that folds upon interaction with a synthetic phospholipid bilayer

Nowicka, Urszula, Hoffman, Morgan, Randles, Leah, Shi, Xiaoshan, Khavrutskii, Lyuba, Stefanisko, Karen, Tarasova, Nadya I., Darwin, K. Heran, Walters, Kylie J.

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2016

Langue:

english

Fichier:

PDF, 580 KB

english, 2016

43

Nucleotide-Dependent Membrane Interaction and Dimerization of K-Ras4B

Jang, Hyunbum, Lu, Shaoyong, Chakrabarti, Mayukh, Khavrutskii, Lyuba, Tarasova, Nadya I., Gaponenko, Vadim, Nussinov, Ruth

Journal:

Biophysical Journal

Année:

2015

Langue:

english

Fichier:

PDF, 59 KB

english, 2015

44

A novel biased antagonist of the eotaxin-CCR3 pathway in eosinophils

Grozdanovic, Milica M., Rousslang, Lee K., Abdelkarim, Hazem, Laffey, Kimberly G., Hitchinson, Ben, Tarasova, Nadya, Gaponenko, Vadim, Ackerman, Steven J.

Journal:

Journal of Allergy and Clinical Immunology

Année:

2017

Langue:

english

Fichier:

PDF, 123 KB

english, 2017

45

Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets

Lu, Xiuxiu, Nowicka, Urszula, Sridharan, Vinidhra, Liu, Fen, Randles, Leah, Hymel, David, Dyba, Marzena, Tarasov, Sergey G., Tarasova, Nadya I., Zhao, Xue Zhi, Hamazaki, Jun, Murata, Shigeo, Burke, Jr

Journal:

Nature Communications

Année:

2017

Langue:

english

Fichier:

PDF, 3.23 MB

english, 2017

46

Small molecule inhibitor of HIV-1 cell fusion blocks chemokine receptor-mediated function

Howard, O. M. Z., Korte, Thomas, Tarasova, Nadya I., Grimm, Michael, Turpin, Jim A., Rice, William G., Michejda, Christopher J., Blumenthal, Robert, Oppenheim, J. J.

Journal:

Journal of Leukocyte Biology

Année:

1998

Langue:

english

Fichier:

PDF, 281 KB

english, 1998

47

New Insights into Mechanisms and Functions of Chemokine (C-X-C Motif) Receptor 4 Heteromerization in Vascular Smooth Muscle

Evans, Ann, Tripathi, Abhishek, LaPorte, Heather, Brueggemann, Lioubov, Singh, Abhay, Albee, Lauren, Byron, Kenneth, Tarasova, Nadya, Volkman, Brian, Cho, Thomas, Gaponenko, Vadim, Majetschak, Matthia

Journal:

International Journal of Molecular Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 4.22 MB

english, 2016

48

Host Directed Therapy for Chronic Tuberculosis via Intrapulmonary Delivery of Aerosolized Peptide Inhibitors Targeting the IL-10-STAT3 Pathway

Upadhyay, Rashmi, Sanchez-Hidalgo, Andrea, Wilusz, Carol J., Lenaerts, Anne J., Arab, Jennifer, Yeh, Joanna, Stefanisko, Karen, Tarasova, Nadya I., Gonzalez-Juarrero, Mercedes

Journal:

Scientific Reports

Année:

2018

Langue:

english

Fichier:

PDF, 2.06 MB

english, 2018

49

Rapid and Accurate Structure-Based Therapeutic Peptide Design using GPU Accelerated Thermodynamic Integration

Garton, Michael, Corbi-verge, Carles, Hu, Yuan, Nim, Satra, Tarasova, Nadya, Sherborne, Brad, Kim, Philip M.

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2018

Langue:

english

Fichier:

PDF, 1.94 MB

english, 2018

50

Structure of E3 ligase E6AP with a proteasome-binding site provided by substrate receptor hRpn10

Buel, Gwen R., Chen, Xiang, Chari, Raj, OâNeill, Maura J., Ebelle, Danielle L., Jenkins, Conor, Sridharan, Vinidhra, Tarasov, Sergey G., Tarasova, Nadya I., Andresson, Thorkell, Walters, Kylie J.

Journal:

Nature Communications

Année:

2020

Fichier:

PDF, 2.55 MB

2020